Assessment of individual kidney function in a dog with congenital anomalies of the urinary tract
16 Apr 2019
Heier, E., Urban, C., Abdellatif, A., Thiel, C., Neiger, R.
A 21-month-old entire female labrador retriever was presented for polyuria, pollakiuria, haematuria and intermittent urinary incontinence. Clinical signs were absent during antibiotic treatment but reoccurred shortly after completion of a treatment course. Investigations detected bilaterally dilated ureters, right renal hypoplasia, left extramural ectopic ureter and right intramural ectopic ureter forming an ureterocoele. Blood tests revealed moderate renal azotaemia. 99mTc-DMSA (technetium-99m-dimercaptosuccinic acid) scintigraphy was used to quantify individual kidney function to carefully consider nephrectomy. The right kidney contributed to less than 2 per cent of the total kidney function. Individual kidney function assessed by 99mTc-DMSA scintigraphy was compared with CT-based renal parenchyma volume as an equivalent to kidney function. In this case both diagnostic imaging techniques resulted in similar individual kidney function percentages. A right-sided nephroureterectomy and a left-sided neoureterocystostomy were performed. Surgical treatment successfully resolved the clinical signs. After surgery the dog’s chronic kidney disease remained stable at International Renal Interest Society chronic kidney disease stage 3.